Can we personalize current available Parkinson’s disease treatment options?
[Greeting] [Title] [Name],
Thank you for taking the time to talk about the current Parkinson’s disease (PD) treatment landscape and your patient population.
To recap:
Current treatments do little to address the variable nature of PD1
Dosing strategies with current carbidopa/levodopa (CD/LD) tablets put patients at risk of imprecise dosing2
Many patients on CD/LD report difficulty managing OFF time and side effects, including dyskinesia3,4
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References: 1. Stoker TB, Greenland JC, eds. Parkinson’s Disease: Pathogenesis and Clinical Aspects. Codon Publications; 2018. 2. Chaudhri K, Kearney M, Di Tanna GL, Day RO, Rodgers A, Atkins ER. Does splitting a tablet obtain the accurate dose?: a systematic review protocol. Medicine (Baltimore). 2019;98(42):e17189. doi:10.1097/MD.0000000000017189. 3. Cabreira V, Soares-da-Silva P, Massano J. Contemporary options for the management of motor complications in Parkinson’s disease: updated clinical review. Drugs. 2019;79(6):593-608. doi:10.1007/s40265-019-01098-w. 4. Tanner CM. Exploring the clinical burden of OFF periods in Parkinson disease. Am J Manag Care. 2020;26(12 suppl):S255-S264. doi:10.37765/ajmc.2020.88517.