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Orenitram is a prescription medicine used to treat pulmonary arterial hypertension (PAH) which is high blood pressure in the arteries of your lungs. Orenitram may improve your ability to exercise. It is not known if Orenitram is safe and effective in children under 18 years of age.
I wrote down some ideas about questions to ask at my next doctor's appointment
Why community matters
Dear [patient name],
Pulmonary arterial hypertension (PAH) is a rare disease, so you may not know anyone who shares your experience. Because hearing from other people may be helpful, watch this video to meet Alecia and Donna. They describe their feelings when they were diagnosed with PAH, their support systems, and how they fit Orenitram into their daily routines.
Reach out to your peers
Connecting with people who also have PAH may help you gain a new perspective. Consider joining a support group or talking with someone one-on-one. PEER Mentors, volunteers with
Watch Alecia's and Donna's stories
Already taking Orenitram?
Orenitram experience, can discuss lifestyle tips and offer emotional support. To be matched with a mentor, call 1(866) 505-7337 or visit PEERNetwork.net.
Celebrate what you've learned
We hope that participating in the Orenitram Patient Support Program has been helpful to you. So far you've received information on
  • PAH and prostacyclin analogue therapy
  • Navigating your PAH-Days
  • Setting your treatment goals
What's next?
Is your current PAH therapy helping you work toward your treatment goals? Remember that your doctor is your best source of information about PAH and Orenitram. Download the Conversation Guide to help you prepare for your next doctor appointment. It may help you solidify your treatment goals and decide what questions you have for your healthcare team.
IMPORTANT SAFETY INFORMATION
Do not take Orenitram if you have severe liver problems.
Before you take Orenitram, tell your healthcare provider if you:
  • Have liver problems, diverticulosis, or any other medical conditions
  • Are pregnant, breastfeeding, and/or plan to become pregnant or breastfeed. It is not known if Orenitram will harm your unborn baby or if Orenitram passes into your breast milk. You and your healthcare provider should decide if you will take Orenitram or breastfeed. You should not do both
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Orenitram and other medicines may affect each other causing side effects. Do not start or stop any new medicine until you check with your healthcare provider. Especially tell your healthcare provider if you take another medicine that contains the same ingredient, treprostinil. Know the medicines you take. Keep a list of them and the dose you take to show to your healthcare provider and pharmacist when you get a new medicine.
Do not change your dose or suddenly stop taking Orenitram without first talking to your healthcare provider. Stopping Orenitram suddenly may cause worsening of your PAH symptoms. If you miss two or more doses of Orenitram, call your healthcare provider. If you take too much Orenitram, call your healthcare provider or go to the nearest hospital emergency room right away.
If Orenitram tablets are not taken whole, they may release too much medicine at one time. This can lead to side effects. Do not split, chew, crush, or break your Orenitram tablets. Do not take Orenitram tablets that are damaged or broken. Take Orenitram with food.
Orenitram can cause serious side effects, including an increased risk of bleeding. This risk could be increased if you are taking blood thinners such as warfarin.
The most common side effects of Orenitram include headache, diarrhea, nausea and flushing. These are not all of the possible side effects of Orenitram. Tell your doctor about any side effects that bother you, get worse over time, or do not go away.
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Call your healthcare provider for medical advice about side effects. You are encouraged to report negative side effects to the FDA at www.fda.gov/medwatch or call 1-800-FDA-1088.
Please see the Full Prescribing Information and Patient Information for Orenitram.
For additional information, visit Orenitram.com or call 1-877-UNITHER (1-877-864-8437).
This information is provided for educational purposes only and is not intended as treatment advice. Consult your healthcare provider for treatment advice.
Sincerely,
Your Orenitram Support Team