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Orenitram is a prescription medicine used to treat pulmonary arterial hypertension (PAH) which is high blood pressure in the arteries of your lungs. Orenitram may improve your ability to exercise. It is not known if Orenitram is safe and effective in children under 18 years of age.
Using the Treatment Diary helped me see that certain foods really do work better for me.
Make your treatment goals more personal
Dear [Name of Patient],
When you started taking Orenitram, you and your healthcare team may have outlined treatment goals. Now is a good time to revisit them. As you assess the progress you're making toward reaching your goals, here are 3 steps you can take to help you stay on track.
one Make your goals personal
  As you think about your treatment goals, consider what things you may want to do that are personally important to you. These may be related to your daily living or your desire to enjoy activities with loved ones.
two Keep notes
  Use the Treatment Diary to record how you feel so you can look back and see what works best for you while taking Orenitram. Seeing what works may help you stay on track.
three Talk to your healthcare team
  Discussing your goals with your healthcare team can help make sure you're all on the same page. Not sure where to start or what questions to ask? Get some ideas from the Conversation Guide.
Conversation Guide
Treament Diary
The most common side effects of Orenitram include headache, diarrhea, nausea and flushing. These are not all of the possible side effects of Orenitram. Tell your doctor about any side effects that bother you, get worse over time, or do not go away.
Remember why you started this path of treatment. Taking Orenitram may improve your ability to exercise. This means you could see improvements in physical activities, such as walking to the mailbox. As you continue, talk to your healthcare team about how you can get the most out of your treatment plan.
IMPORTANT SAFETY INFORMATION
Do not take Orenitram if you have severe liver problems.
Before you take Orenitram, tell your healthcare provider if you:
  • Have liver problems, diverticulosis, or any other medical conditions
  • Are pregnant, breastfeeding, and/or plan to become pregnant or breastfeed. It is not known if Orenitram will harm your unborn baby or if Orenitram passes into your breast milk. You and your healthcare provider should decide if you will take Orenitram or breastfeed. You should not do both
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Orenitram and other medicines may affect each other causing side effects. Do not start or stop any new medicine until you check with your healthcare provider. Especially tell your healthcare provider if you take another medicine that contains the same ingredient, treprostinil. Know the medicines you take. Keep a list of them and the dose you take to show to your healthcare provider and pharmacist when you get a new medicine.
Do not change your dose or suddenly stop taking Orenitram without first talking to your healthcare provider. Stopping Orenitram suddenly may cause worsening of your PAH symptoms. If you miss two or more doses of Orenitram, call your healthcare provider. If you take too much Orenitram, call your healthcare provider or go to the nearest hospital emergency room right away.
If Orenitram tablets are not taken whole, they may release too much medicine at one time. This can lead to side effects. Do not split, chew, crush, or break your Orenitram tablets. Do not take Orenitram tablets that are damaged or broken. Take Orenitram with food.
Orenitram can cause serious side effects, including an increased risk of bleeding. This risk could be increased if you are taking blood thinners such as warfarin.
The most common side effects of Orenitram include headache, diarrhea, nausea and flushing. These are not all of the possible side effects of Orenitram. Tell your doctor about any side effects that bother you, get worse over time, or do not go away.
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Call your healthcare provider for medical advice about side effects. You are encouraged to report negative side effects to the FDA at www.fda.gov/medwatch or call 1-800-FDA-1088.
Please see the Full Prescribing Information and Patient Information for Orenitram.
For additional information, visit Orenitram.com or call 1-877-UNITHER (1-877-864-8437).
This information is provided for educational purposes only and is not intended as treatment advice. Consult your healthcare provider for treatment advice.
Sincerely,
Your Orenitram Support Team