Tips and information to help you on your treatment journey.
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What is Orenitram?
Orenitram (treprostinil) is a prescription medicine used to treat pulmonary arterial hypertension (PAH) which is high blood pressure in the arteries of your lungs. Orenitram may improve your ability to exercise. It is not known if Orenitram is safe and effective in children under 18 years of age.
IMPORTANT SAFETY INFORMATION  |  FULL PRESCRIBING INFORMATION  |  PATIENT INFORMATION
WELCOME TO THE ORENITRAM
SUPPORT PROGRAM
Congratulations! By enrolling in this support program, you’ve made an important decision about your health. We hope you’ll find this program to be a helpful resource in learning more about PAH and treatment with Orenitram.
CHECK OUT THIS HELPFUL WORKBOOK:
PREPARING FOR ORENITRAM
Stay informed during your treatment journey
We understand that beginning a new treatment can sometimes feel overwhelming. But, learning all you can about your Orenitram treatment may make you feel more prepared. The Orenitram website is a great resource that you and your loved ones can visit and explore any time for more information.
It’s important to remember that you have many resources available to you. Your doctor, nurses, and specialty pharmacy providers are available to help you incorporate Orenitram into your treatment regimen. And United Therapeutics provides additional information through this Support Program. The materials you’ll receive are packed with useful information and resources.
Check your inbox for periodic e-newsletters and watch your mail for materials sent as part of this program.
IMPORTANT SAFETY INFORMATION
Do not take Orenitram if you have severe liver problems.
Before you take Orenitram, tell your healthcare provider if you:
  • Have liver problems, diverticulosis, or any other medical conditions
  • Are pregnant, breastfeeding, and/or plan to become pregnant or breastfeed. It is not known if Orenitram will harm your unborn baby or if Orenitram passes into your breast milk. You and your healthcare provider should decide if you will take Orenitram or breastfeed. You should not do both
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Orenitram and other medicines may affect each other causing side effects. Do not start or stop any new medicine until you check with your healthcare provider. Especially tell your healthcare provider if you take another medicine that contains the same ingredient, treprostinil. Know the medicines you take. Keep a list of them and the dose you take to show to your healthcare provider and pharmacist when you get a new medicine.
Do not change your dose or suddenly stop taking Orenitram without first talking to your healthcare provider. Stopping Orenitram suddenly may cause worsening of your PAH symptoms. If you miss two or more doses of Orenitram, call your healthcare provider. If you take too much Orenitram, call your healthcare provider or go to the nearest hospital emergency room right away.
If Orenitram tablets are not taken whole, they may release too much medicine at one time. This can lead to side effects. Do not split, chew, crush, or break your Orenitram tablets. Do not take Orenitram tablets that are damaged or broken. Take Orenitram with food.
Orenitram can cause serious side effects, including an increased risk of bleeding. This risk could be increased if you are taking blood thinners such as warfarin.
The most common side effects of Orenitram include headache, diarrhea, nausea and flushing. These are not all of the possible side effects of Orenitram. Tell your doctor about any side effects that bother you, get worse over time, or do not go away.
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You may report side effects to the FDA at www.fda.gov/MedWatch or call 1-800-FDA-1088.
Please see Full Prescribing Information and Patient Information.
For additional information about Orenitram, visit www.orenitram.com or call 1-877-UNITHER (1-877-864-8437).
This information is provided for an informational purpose and is not intended as treatment advice. Patients should consult a healthcare professional for treatment advice.
Orenitram is a registered trademark of United Therapeutics Corporation.
© 2018 United Therapeutics Corporation. All rights reserved. US/ORE/0230
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Research Triangle Park, NC 27709
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