Ride the wave to clearer skin 🌊

S1:	Ride the wave to clearer skin 🌊
S2:	Is it time to schedule your next appointment? ⏰
S3:	Discover the benefits of blue light therapy

P1:	Talk with your doctor about how blue light therapy may help
P2:	Continue on your journey toward clearer skin with blue light therapy
P3:	A convenient treatment to prevent skin cancer

[Have you been prescribed blue light therapy? Yes

]
[Have you booked your next blue light therapy treatment? Yes

]

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Hello [Name],

You have been prioritizing your skin health—nicely done!

GUIDE

If you notice sunspots on your skin, they could be actinic keratoses (AKs). Regular skin checks are crucial for managing and treating these areas. AKs can persist and recur, but with the help of your dermatologist, you can maintain your skin health. Schedule regular appointments to address any concerns you may have.

If you haven’t tested your AK IQ yet, quiz yourself here.

MAINTAIN

Even after treatment, actinic keratoses (AKs) can reappear. This is because they form in areas of the skin that have been chronically exposed to ultraviolet (UV) radiation. Regular skin exams are crucial for monitoring new and recurring AKs and may help to prevent the risk of skin cancer.

You can achieve up to 100% clearance of AKs in just 1-2 treatments, but more people experienced clearer skin after 2 treatments rather than 1 alone.

GUIDE

Interested in talking with a doctor about blue light therapy?

MAINTAIN

Are you prepared for your next treatment with LEVULAN^® KERASTICK^® + BLU-U^®?

Do you know someone who may have AK sunspots?

Encourage them to sign up for BLU-U + YOU^™ to receive customized resources about their skin health using this link.

Cloudy with a chance of UV rays?!

Even on cloudy or cool days, UV rays can reach you by reflecting off surfaces such as water, cement, sand, and snow.

IMPORTANT SAFETY INFORMATION

PATIENT INFORMATION

LEVULAN KERASTICK (aminolevulinic acid HCl) is for use only as an in-office treatment. LEVULAN KERASTICK treatment is given by a healthcare provider only and is not for use at home.

What is LEVULAN KERASTICK?

LEVULAN KERASTICK is a prescription medicine applied in your doctor's office and used on the skin in combination with blue light treatment (BLU-U Blue Light Photodynamic Therapy or PDT) for the treatment of minimally to moderately thick actinic keratoses (AKs) of the face, scalp, or arms.

It is not known if LEVULAN KERASTICK is safe and effective in children under 18 years of age.

Who should not receive LEVULAN KERASTICK treatment?

Do not receive LEVULAN KERASTICK treatment if you:

•	are allergic to aminolevulinic acid HCl or to any of the ingredients in LEVULAN KERASTICK.
•	have porphyria or are allergic to porphyrins
•	have a skin sensitivity to blue light.

Before receiving LEVULAN KERASTICK treatment, tell your healthcare provider about all of your medical conditions, including if you:

•	have blood clotting problems
•	are pregnant or plan to become pregnant. It is not known if LEVULAN KERASTICK will harm your unborn baby.
•	are breastfeeding or plan to breastfeed. It is not known if LEVULAN KERASTICK passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during LEVULAN KERASTICK treatment.
•	Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. LEVULAN KERASTICK and other medicines may affect each other.

How will I receive LEVULAN KERASTICK treatment?

•

LEVULAN KERASTICK treatment is received in two parts:

–	Your healthcare provider will apply LEVULAN KERASTICK topical solution to your skin lesions. You should not wash the treated areas before you return to your healthcare provider for blue light treatment.
–	After the prescribed amount of time you will return to your healthcare provider for blue light treatment. If you cannot return for blue light treatment on schedule, avoid sunlight and bright indoor light for at least 40 hours after LEVULAN KERASTICK topical solution has been applied.

•

During blue light treatment, you will likely feel tingling, stinging, prickling, or burning of the treated areas.

What should I avoid during LEVULAN KERASTICK treatment?

After LEVULAN KERASTICK topical solution is applied to your skin you should avoid sunlight or bright indoor light (such as examination lights, operating room lights, tanning beds, or lights that are close to you) for 40 hours. During this time, the treated areas of your skin will become sensitive to light.

Exposure to light during this time may cause you to feel a burning or stinging sensation and may cause your treated lesions to become red or swollen. You should wear appropriate protective apparel such as a wide-brimmed hat, long sleeve shirt, and gloves to protect your treated skin from sunlight and other bright light.

Sunscreen will not protect the treated areas of your skin against sensitivity to light.

What are the possible side effects of LEVULAN KERASTICK?

LEVULAN KERASTICK may cause serious side effects, including:

•	Temporary memory problems: Temporary memory problems have happened during treatment with LEVULAN KERASTICK in combination with BLU-U Blue Light Photodynamic Therapy Illuminator. You or your family members or caregiver should call your healthcare provider right away if you develop any problems with memory, confusion, or disorientation during treatment.
•	Sensitivity to light
•	Skin irritation. LEVULAN KERASTICK topical solution contains alcohol and may cause skin irritation if covered or bandaged for longer than 3 hours.

The common side effects of LEVULAN KERASTICK include:

Local skin reactions including redness, swelling, stinging and burning, scaling, crusting, oozing, pustules, welts, scabbing, itching, erosion, changes in skin color, bleeding, tenderness, changes in the sense of touch, and dryness.

These are not all the possible side effects of LEVULAN KERASTICK.

Call your doctor for medical advice about side effects.

You may report side effects to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Please see full Prescribing Information.

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Sun Pharmaceutical Industries, Inc.

29 Dunham Road

Billerica, MA 01821

PM-US-LEV-0754 10/24